
Editor-in-Chief: Alaa Abd-Elsayed, MD, PhD

Abstract
- 2025;9;115-118 Nanotechnology Pain Patch Relieves Chronic Back Pain: A Case Report
Case Report
Danielle Levin, MD, Sarah Levin, BA, Abhin Shah, BS, and Martin Acquadro, MD.
BACKGROUND: Low back pain is a debilitating symptom that may develop into a refractory chronic condition, resistant to physical, medical, psychological, and/or interventional therapy options. We would like to share the first report of a nanotechnology pain patch providing > 90% chronic back pain relief for 3 months.
CASE REPORT: A 75-year-old man with chronic low back pain secondary to L2-L3 disc herniation suffered from pain for > 35 years. He found physical therapy, baclofen, low-dose opioids, and lumbar epidural steroid injection ineffective. A trial of a nanotechnology pain patch (nCAP Signal Relief Patch) worn daily provided the patient with consistent 90% to 100% back pain relief and enabled the patient to have significant functional improvement.
CONCLUSIONS: This case report demonstrates that the nCAP Signal Relief Patch could be a simple, safe, noninvasive, and effective treatment option for those affected by chronic low back pain.